Postdoc in Protein chemistry at Finsen Laboratory/BRIC


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We are looking for a highly motivated and dynamic researcher for a 3-year position, who will commence full-time in our dynamic research group preferably on 1 April 2021 or after agreement. Our current research focus concerns proteins involved in matrix degradation (during cancer invasion and metastasis) and in intravascular lipid metabolism.


Information on the department and our group can be found at: www.bric.ku.dk/research-groups/Research/ploug_group/

Our research
We are a small research group at the Finsen Laboratory/BRIC and we focus on biochemical and biophysical characterization of disease relevant proteins and their ligands. We provide a detailed understanding on how a given pathway maintains homeostasis in normal physiology and why certain aberrations – such a missense mutations and natural polymorphisms – cause dysregulation in pathophysiology. Ultimately, we seek to use this information in translational pipelines – e.g. the clinical phase-2 trials with our uPAR-targeting peptide for non-invasive PET imaging of uPAR-expression in chronic inflammation and solid cancer (Theranostics 3, 13 467; Theranostics 3, 2013, 618; Theranostics 5, 2015, 1066). For references on our research in intravascular lipid metabolism (Cell Metabolism 30 (2019) 51-65). 

We offer a highly dynamic and interactive research environment with an extensive national and international research network. Our attention is strictly focused on the scientific research and we seek to launch a joint effort to advance and keep momentum in our research—thus exploiting the synergy created in that process. And this is great fun! 

Your job
Your tasks would be – in synergy with members of our research group and collaborators – to explore structure-function relationships in proteins involved in intravascular lipolysis that is decisive for their function in normal physiology and why they are dysfunctional in pathophysiology. We expect you to become family with and critically evaluate the literature on intravascular lipolysis as well as on the applied biophysical methods. Your results should be discussed openly within the research group and disseminated to the scientific community by high quality publications.


Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:

Essential experience and skills:

  • You have a PhD in Life Science
  • You are highly experienced in working with structure-function relationships in purified proteins, preferably using an array of biophysical methods such as SPR, MST, SAXS, and nano-DSF.
  • You have an active interest in pursuing underlying mechanisms in disease related proteins involved in intravascular lipolysis
  • Proven ability to envision, plan and execute a research project  
  • Proficient communication skills and ability to work in teams to foster synergy in creativity
  • Excellent English skills written and spoken

Desirable experience and skills:

  • Experience in conducting in vivo studies in mice is an advantage but not prerequisite.

Place of employment
The place of employment is at Finsen Laboratory, BRIC, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and contemporary equipment for protein analysis e.g., 2 Biacore instruments, MALDI-TOF/TOF, nano-DSF, MST, and two HPLC-one with MALS detection.


Terms of employment
The employment as postdoc is a full time and fixed-term position for 3 years. Starting date is 1st April 2021

Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Currently, the monthly salary starts at 34,600 DKK/ approx. 4,650 Euro (April 2020-level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of December 2019.

Questions
For further information please contact Michael Ploug, m-ploug@finsenlab.dk

Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).

Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore your application must include the following documents/attachments – all in PDF format:

1. Motivated letter of application (max. one page).

2. CV incl. education, work/research experience, language skills and other skills relevant for the position.

3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.

4. List of publications.

Application deadline:   19 January 2021, 23.59pm CET

 We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

 You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/

 The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

 Interviews are expected to be held in week 7/8 2021.

University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of age, disability, gender, nationality, race, religion or sexual orientation. Appointment will be based on merit alone.

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