Pharmacy
| Location: | University Park |
| Salary: | £29,762 to £38,474 per annum (pro rata if applicable) depending on skills and experience (minimum £33348 with relevant PhD). |
| Closing Date: | Tuesday 11 July 2023 |
| Reference: | SCI225623 |
We are currently seeking a Research Associate/Fellow to join a multidisciplinary research project funded Great Ormond Street Hospital (GOSH) Charity to undertake research on the design and development of a novel class gene therapy for the genetic correction of Rett Syndrome (RTT) by gene augmentation and expression self-regulation strategies. The successful candidate will join highly motivated and well-funded research teams within the School of Pharmacy, located in state-of-the-art facilities in the multidisciplinary University of Nottingham Biodiscovery Institute (BDI) on the main University Park campus. This project is in collaboration with Johns Hopkins University (JHU) USA, and the University of Edinburgh.
The post will design, develop and execute formulation of gene delivery peptide nanoparticles. These activities involve: 1) nanoparticle formulation/characterisation, 2) engineer vectors for testing of expression dynamics, and 3) in vitro assessments using cell culture gene delivery. The successful candidate will be a cell-culture and molecular biology expert, and have experience of gene expression regulation and engineering of feedback systems to control levels of transgene output and longevity.
Candidates should have, or be close to completion of, a PhD in molecular and/or cell biology, together with a keen interest in neuroscience] medicine and gene therapy/ editing.
This post will be offered on a fixed term contract for 3 years if a start date of 1st September 2023 is met; if not, the end date must be 31st August 2026. Hours of work are full time (36.25 hours). Job share arrangements may be considered.
We pride ourselves on the collegial and support culture created by our staff. We are dedicated to creating an environment which enables our staff to thrive and achieve their potential. Our commitment to Equality and Diversity has been recognised in the awarding of an Athena SWAN Silver Award.
Informal enquiries may be addressed to Dr James Dixon (tel: 0115 748 6313 or Email: james.dixon@nottingham.ac.uk). Please note that applications sent directly to this Email address will not be accepted.