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The Department of Medical Biochemistry and Microbiology (IMBIM) at Uppsala University provides a broad international environment for research and teaching. Research at IMBIM) broadly spans the areas of biochemistry, cell and molecular biology, tumour biology, comparative genetics, functional genomics, immunology, bacteriology, and virology. The research is essentially of fundamental nature, but with relevance and application in health and disease in both animals and humans. More info: https://www.imbim.uu.se/research-areas/.
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Project description
We are looking for a highly motivated person, with an ability to work independently and in collaboration with other groups. The candidate should have a strong interest in pursuing a PhD degree in the field of protein science with a focus on protein evolution and interactions.
The project will address fundamental questions regarding evolution of protein structure and function. The goal is to define principles governing evolution of new proteins. The work includes heterologous expression and purification of proteins and characterization of their structure, stability and interactions using a range of biophysical and bioinformatics methods and analyses.
Qualifications
The person we are looking for should have a master’s degree or equivalent (240 ECTS) in molecular biology, biochemistry, structural biology or similar, providing basic theoretical and practical knowledge. Experience in working with proteins should be demonstrated through a MSc project.
The applicant must be fluent in written and spoken English (see entry requirements at: https://www.uu.se/en/study/masters-studies/application/entry-requirements). The candidate is expected to take initiative driving the project, but also to collaborate within the group and with other groups. Emphasis will be given on personal qualities, including analytical capacity, accuracy, flexibility and collaborative skills.
Additional merits or desired skills
The ideal candidate would be able to express and purify proteins in E. coli and perform basic characterization of the proteins. Furthermore, experience of protein interaction techniques such as isothermal titration calorimetry, fluorescence polarization (or other methods), and structural methods (circular dichroism, X-ray crystallography, NMR or Cryo-EM) are meritorious.
The selection is based on the following criteria
Completion of the above qualifications, grades in relevant courses, suitability of the courses to the research program, previous experience in working and/or performing research in the wider area that relates to the project described above. An integrated assessment of the applicant is generated in order to employ the best possible candidate that can succeed in the doctoral studies and contribute to a positive development of the department and the research program.
To be employed as a PhD student, the applicant must be accepted in a doctoral program. Information concerning doctoral education, requirements and rules of admission can be found at Medicine and Pharmacy – Uppsala University (uu.se)
The length of the study period for full time employment is a maximum of four years. Terms for graduate studies can be found in Högskoleförordningen 5 kap 1-7 §§ and in: Uppsala University’s rules and guidelines.
About the employment
The employment is a temporary position according to the Higher Education Ordinance chapter 5 § 7. Scope of employment 100 %. Starting date as soon as possible or as agreed. Placement: Uppsala
For further details, please contact: Per Jemth, Per.Jemth@imbim.uu.se
Application: Please submit your application using the Uppsala University application portal, by including a CV, a letter describing your research interest and skills, publications or a copy of master thesis or equivalent, contact information of two referees (phone number and e-mail address).
You are welcome to submit your application no later than August 21, 2023, UFV-PA 2023/2581.
Are you considering moving to Sweden to work at Uppsala University? If so, you will find a lot of information about working and living in Sweden at www.uu.se/joinus. You are also welcome to contact International Faculty and Staff Services at ifss@uadm.uu.se.
Please do not send offers of recruitment or advertising services.
Submit your application through Uppsala University’s recruitment system.
Placement: Department of Medical Biochemistry and Microbiology
Type of employment: Full time , Temporary position
Pay: According to local agreement
Number of positions: 1
Working hours: 100
Town: Uppsala
County: Uppsala län
Country: Sweden
Union representative: Saco-rådet saco@uadm.uu.se
ST/TCO tco@fackorg.uu.se
Seko Universitetsklubben seko@uadm.uu.se
Number of reference: UFV-PA 2023/2581
Last application date: 2023-08-21