Uppsala University is a comprehensive research-intensive university with a strong international standing. Our ultimate goal is to conduct education and research of the highest quality and relevance to make a long-term difference in society. Our most important assets are all the individuals whose curiosity and dedication make Uppsala University one of Sweden’s most exciting workplaces. Uppsala University has over 54,000 students, more than 7,500 employees and a turnover of around SEK 8 billion.
The Department of Cell and Molecular Biology is divided into seven research programs that all focus on different areas within cell and molecular biology: computational biology and bioinformatics, microbiology and immunology, molecular biology, molecular biophysics, molecular evolution, molecular systems biology and structural biology. The scientific basis of what we do is within ‘biology’, but our research overlaps with other fields such as medicine, computer science, mathematics, chemistry, engineering and physics. The department has over 200 employees with around 60 PhD students. Please read more about the department’s work at https://icm.uu.se.
The postdoctoral fellow will be located in Suparna Sanyal’s research group in the Molecular Biology program https://www.icm.uu.se/molecular-biology/sanyal-lab/. The group’s research in based on understanding the mechanisms of protein synthesis in bacteria and eukaryotes with a particular focus on antibiotic resistance and pathogenic bacteria and protozoa. Our publications are available at https://scholar.google.com/citations?hl=en&user=5eTR4gkAAAAJ.
Read more about our benefits and what it is like to work at Uppsala University
Duties
The postdoctoral fellow will study “translation initiation in pathogenic protozoa Giardia intestinalis using fast kinetics methods and high-resolution cryo-electron microscopy”. For that the postdoc will require to reconstruct in the test-tube a minimal translation system of Giardia by purifying different components of the translation machinery of the protozoa e.g. ribosomes, tRNA, eIF4F complex, eIF1, eIF1A and eIF2 translation factors.
In addition, the postdoc will screen in silico, drugs targeting protozoan and bacterial ribosomes.
Requirements
PhD degree in Molecular biology, Structural biology, Biotechnology or a foreign degree equivalent to a PhD degree in the same area. The degree needs to be obtained by the time of the decision of employment. Those who have obtained a PhD degree three years prior to the application deadline are primarily considered for the employment. The starting point of the three-year frame period is the application deadline. Due to special circumstances, the degree may have been obtained earlier. The three-year period can be extended due to circumstances such as sick leave, parental leave, duties in labour unions, etc.
The candidate should be highly motivated to conduct research and communicate the research results to the scientific community.
The postdoctoral fellow should also be able to conduct research and collaborate in an international research environment.
Good knowledge in speaking, reading scientific literature and writing articles in English is beneficial for this position.
Additional qualifications
The candidate must have experience in solving the cryo-EM structure of ribosomes. In addition, the candidate should have experience in in silico docking and screening of chemical compounds.
The capacity of making scientific illustrations using Adobe Photoshop/Illustrator and BiorenderTM will be considered as a merit.
About the employment
The employment is a temporary position of 2 years according to central collective agreement. Scope of employment 100 %. Starting date is negotiable. Placement: Uppsala
For further information about the position, please contact: Prof. Suparna Sanyal, +46-704250340, suparna.sanyal@icm.uu.se
Please submit your application by 10 August 2023, UFV-PA 2023/2667.
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Submit your application through Uppsala University’s recruitment system.
Placement: Department of Cell and Molecular Biology
Type of employment: Full time , Temporary position
Pay: Individual salary
Number of positions: 1
Working hours: 100%
Town: Uppsala
County: Uppsala län
Country: Sweden
Union representative: Seko Universitetsklubben seko@uadm.uu.se
ST/TCO tco@fackorg.uu.se
Saco-rådet saco@uadm.uu.se
Number of reference: UFV-PA 2023/2667
Last application date: 2023-08-10