Project: Postdoctoral position in the circuit neuromodulation of motor action and decision making

Commitment & contract: temporary contract until 2025

Location: CCT@Morego

WHO WE ARE

At IIT, we work enthusiastically to develop human-centered Science and Technology to tackle some of the most pressing societal challenges of our times and transfer these technologies to the production system and society. Our Genoa headquarter is strictly inter-connected with our 11 centers around Italy and two outer-stations based in the US for a truly interdisciplinary experience.

YOUR TEAM

You will be working in a multicultural and multi-disciplinary group, where molecular, cellular and behavioural neuroscientists collaborate, each with their own expertise, to carry out common research.

The Neuromodulation of Cortical and Subcortical Circuits  Research Line is coordinated by Raffaella Tonini, who has extensive experience in Cellular and Circuit Neuroscience.

Research activity in the lab aims to resolve the fundamental mechanisms of synaptic neuromodulation and to investigate the spatiotemporal dynamic of behaviorally relevant neuromodulatory signals at circuit and system resolution.

You will investigate how midbrain neuromodulatory nuclei convey internal-state (positive or negative valence) information to motor control regions (striatum), thereby influencing action control, both in health and disease state (psychomotor and affective disorders).

To this purpose, you will apply neurophysiological, optogenetic and chemogenetic approaches (ex vivo and in vivo) to study how noradrenaline, serotonin- and endocannabinoid signals interact to modulate the activity of neurons as well as the astrocyte-neuron crosstalk. These studies will be implemented by using state-of-the art imaging techniques (miniscope imaging and fiber photometry) to monitor neuronal and astrocytic activity along with neuromodulators during behavioral paradigms.

ESSENTIAL REQUIREMENTS

  • A PhD in Physiology, Neuroscience, Physics or related disciplines
  • Documented experience in neurophysiology and optogenetics, combined with viral-based approaches to deconstruct and manipulate neuronal circuits ex-vivo and in-vivo; confocal microscopy.
  • A strong publication record
  • The ability to properly report, organize and publish research data
  • Good command in spoken and written English

ADDITIONAL SKILLS

  • Experience on large-scale neuronal imaging in-vivo (miniscope imaging and fiber photometry) and programming (Python or MATLAB) will be highly valued.
  • Signal processing expertise appropriate for the analysis of neuronal activity
  • Good communication skills
  • Strong problem solving attitude
  • High motivation to learn
  • Spirit of innovation and creativity
  • Good in time and priority management
  • Ability to work in a challenging and international environment
  • Ability to work independently and collaboratively in a highly interdisciplinary environment

SALARY & BENEFITS

  • Competitive salary package for international standards
  • Private health care coverage
  • Wide range of staff discounts
  • Candidates from abroad or Italian citizens who permanently work abroad and meet specific requirements, may be entitled to a deduction from taxable income of up to 90% from 6 to 13 years

 WHAT’S IN FOR YOU?

  • An equal, inclusive and multicultural environment ready to welcome you with open arms. Discrimination is a big NO for us!
  • We like contamination and encourage you to mingle and discover what other people are up to in our labs! 
  • If paperwork is not your piece of cake, we got you! There’s a specialized team working to help you with that, especially during your relocation.
  • If you want your work to have a real impact, in IIT you will find an innovative and stimulating culture that drives our mission to contribute to the improvement and well-being of society!
  • We stick to our values! Integrity, courage, societal responsibility and inclusivity are the values we believe in. They define us and our actions in our everyday life. They guide us to accomplish IIT mission.

Please submit your application using the online form and including a detailed CV, university transcripts, cover letter (outlining motivation, experience and qualifications) and contact details of 2 references.

Application’s deadline: August 10, 2022.

We inform you that the information you provide will be used solely for the purposes of evaluating and selecting professional profiles in order to meet the requirements of Istituto Italiano di Tecnologia.

Your data will be processed by Istituto Italiano di Tecnologia, based in Genoa, Via Morego 30, acting as Data Controller, in compliance with the rules on protection of personal data, including those related to data security.

Please also note that, pursuant to articles 15 et. seq. of European Regulation no. 679/2016 (General Data Protection Regulation), you may exercise your rights at any time by contacting the Data Protection Officer (phone Tel: +39 010 28961 – email: dpo@iit.it ).

Primary Location

 GENOVA

Job

 Postdoc

Organization

 Neuromodulation of Cortical and Subcortical Circuits

Job Posting

 Jul 8, 2022, 11:25:58 AM

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