Developmental and Evolutionary Biology & Genetics Immunobiology and Infection Biology & Medicine Structural and Cell Biology

hD Student (m/f/d) & Postdoctoral Researcher (m/f/d) | Systems biology of ubiquitin: from chemistry to mass spec to cellular regulation.

The departments of ‘Molecular Machines and Signaling’ and ‘Proteomics and Signal Transduction’ at the Max-Planck-Institute of Biochemistry headed by Brenda Schulman and Matthias Mann seek highly motivated and talented researchers (m/f/d) for two positions, PhD Student (m/f/d) and Postdoctoral Researcher (m/f/d).

Project Overview

The joint projects between Schulman and Mann departments build on their longstanding expertise in the ubiquitin field and proteomics. The projects combine developing innovative chemical and biological probes with cutting-edge mass spectrometry and cell biology, to explore active ubiquitin E3 ligase networks in cells. Our aims are to discover novel complexes, molecular and structural mechanisms, and principles of cellular regulation by ubiquitin-proteasome system.

We focus on diverse areas of biology where unearthing signaling via the ubiquitin system is pivotal. These include metabolic signaling, immune responses, neuronal function and degeneration, cancer cell biology, and infection. The anticipated outcomes include deep insights into cellular networks, identification of potential therapeutic targets, and advancements in methodologies for interactomics, proteoforms, and complexosomes studies. We refine approaches and questions based on experimental findings to make impactful discoveries and develop cutting-edge new methods.


  • Degree in biochemistry, chemistry, molecular biology, biotechnology or relevant fields:
    • MSc or equivalent degree required for PhD students (m/f/d)
    • PhD or equivalent degree required for postdoctoral researchers (m/f/d)
  • Strong background in multiple of the following areas: protein biochemistry, protein design, structural biology, cell biology and/or mass spectrometry
  • Multidisciplinary, experimentalist mindset, dedicated to scientific rigor
  • Excellence in both written and spoken English
  • High proficiency in working autonomously in a fast-paced and dynamic environment
  • Outstanding team player (m/f/d), with a strong commitment and work ethic, keen to contribute within a multi-disciplinary, collaborative and international team setting, with desire to both drive and support multiple projects

Our offer

The successful applicants (m/f/d) will have the opportunity to join renowned and well-equipped laboratories led by two esteemed scientists, fostering a dynamic international research environment known for its collaborative and collegial scientific atmosphere. Under the mentorship of these distinguished researchers, they will pursue collaborative projects at the interface of molecular design, chemistry, structural biology, and biological mass-spectrometry with potential biomedical applications.

Positions are available from the earliest date possible. Salaries and social security benefits will adhere to German Collective Wage Agreement for Public Sector Employees (TVöD) based on experience and qualifications. PhD students (m/f/d) will join us as part of the International Max Planck Research School for Molecules of Life (IMPRS-ML).

Max Planck Insitute of Biochemistry is situated within the Campus Martinsried, a suburb of Munich, hosting multiple academic institutions and numerous biotech companies. Munich stands out as one of Europe’s premier hubs for life scientists (m/f/d) and AI/machine learning, and offering an exceptional quality of life. Its unique blend of rich culture, picturesque surroundings, excellent healthcare, and thriving professional opportunities make it an ideal city to live and work in.

The Max Planck Society strives for gender equality and diversity. We welcome applications from all backgrounds. Furthermore, we are committed to increasing the representation of individuals with disabilities in our workforce and therefore encourage applications from such qualified individuals.

Your application

Please, submit your application to, including the following documents:

  • Curriculum vitae
  • Letter of motivation
  • Contact details of two academic referees

Applications will be accepted immediately and will continue until the positions are filled. We look forward to receiving your application.

For any inquiries about the positions, please contact

Leave a Reply